Mesenchymal Stem Cell Transplantation for Spinal Cord Injury: Current Status and Prospects

Promise of Autologous Bone Marrow Stem Cell Transplantation to Patients with Spinal Cord Injury-Current Status

Due to rapid industrialization, population raise and development of real estate business results to build of enormous constructions, which leads to the injuries of spinal cord. The burden of spinal cord injury induced limb paralysis increasing every year in India. Increasing vehicular traffic has caused numerous road traffic accidents. Spinal cord injury (SCI) affects all aspects of a patient’s...

Human umbilical cord blood-derived mesenchymal stem cell transplantation for the treatment of spinal cord injury

The aim of the present study was to investigate the effects of human umbilical cord blood-derived mesenchymal stem cell (HUCB-MSC) transplantation on the functional restoration of spinal cord injury (SCI). A total of 46 adult Wistar rats were randomly divided into three groups: Injury (n=15), control (n=15) and transplantation (n=16). A SCI model was established using the modified Allen's metho...

Repair of Spinal Cord Injury by Co-Transplantation of embryonic Stem Cell-Derived Motor Neuron and Olfactory Ensheathing Cell

Background: The failure of regeneration after spinal cord injury (SCI) has been attributed to axonal demyelination and neuronal death. Cellular replacement and white matter regeneration are both necessary for SCI repair. In this study, we evaluated the co-transplantation of olfactory ensheathing cells (OEC) and embryonic stem (ES) cell-derived motor neurons (ESMN) on contused SCI. Methods: OEC...

Mesenchymal Stem Cell Therapy for Apoptosis After Spinal Cord Injury

Hematopoietic stem cell transplantation in China: current status and prospects.

During the past four decades, a substantial progress has been made in the field of hematopoietic stem cell transplantation (HSCT). From July, 2007 to December, 2010, a transplant survey from 42 HSCT units indicates that the types of transplantation performed are related identical (43%), related mismatched/haploidentical (28%), unrelated donor matched (11%), unrelated donor mismatched (7%), umbi...